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Peptide Library / Growth Hormone / Performance

GHRP-6

Growth Hormone Releasing Peptide-6

GHRP-6 Research Protocol

Complete Research Guide 4 min read1 peer-reviewed references

Quickstart Overview

GHRP-6 is a first-generation hexapeptide growth-hormone secretagogue known for pronounced appetite stimulation via the ghrelin receptor. It raises GH strongly and is sometimes used specifically for its hunger-inducing and gut-motility effects.

Reconstitution
Add 2.0 mL bacteriostatic water to a 5 mg vial → 2.5 mg/mL
Literature Range
100–300 mcg per administration
Measuring Reference
At 2.5 mg/mL: 100 mcg = 0.04 mL = 4 units
Frequency
1–3× daily
Route (studies)
Subcutaneous
Cycle
8–12 weeks

Scientific Data

Molecular Formula
—
Molecular Weight
873.44 Da
Sequence
His-D-Trp-Ala-Trp-D-Phe-Lys-NH2
Sequence Length
22
CAS
Research compound
Peptide Family
GHRP
Half-life
Refer to published literature
Solubility
Bacteriostatic water, sterile saline
Storage
Lyophilized: -20°C. Reconstituted: 2–8°C, use within 2–4 weeks.
Appearance
White lyophilized powder
Standard: 5 mg vial · 2 mL diluent

Dosing & Reconstitution Guide

Interactive Reconstitution
Adjust vial size, diluent and target dose. Results update live.
Full Precision Calculator →
Concentration
2.50 mg/mL
Draw Volume
0.040 mL
Syringe Units
4.0 U
Doses / Vial
50

Units assume a U-100 insulin syringe (100 units = 1 mL). The hungriest of the GHRPs — appetite stimulation is the signature effect.

Frequency: 1–3× daily, fasted

Reconstitution Steps

  1. 1Allow the lyophilized vial and bacteriostatic water to reach room temperature (~15 min).
  2. 2Swab both vial stoppers with a fresh 70% isopropyl alcohol pad and let them dry.
  3. 3Draw 2.0 mL of bacteriostatic water into a mixing syringe.
  4. 4Insert at an angle and let the water run slowly down the glass wall — never directly onto the powder.
  5. 5Gently swirl (do not shake) until the solution is completely clear.
  6. 6Label with date and concentration (mg/mL) and refrigerate at 2–8 °C immediately.

Supplies Needed

Planning example for a 12-week protocol at approximately 300 mcg per day.

Peptide (5 mg vials)
Estimate vials from total mass: 300 mcg/day × 84 days.
Bacteriostatic Water
One 10–30 mL vial typically covers a full cycle.
Insulin Syringes (U-100)
One per administration (29–31 G, 0.3–0.5 mL).
Alcohol Swabs
Two per administration (vial + site).
Sharps Container
Required for safe disposal.

Protocol Overview

Goal
Model ghrelin-receptor GH release with strong appetite stimulation.
Schedule
Daily, 8–12 weeks.
Dose Range
100–300 mcg per dose.

Dosing Protocol

Start
100 mcg 1–3× daily
Target
100–300 mcg per dose
Frequency
Pre-bed, fasted AM, post-training
Cycle Length
8–12 weeks
Timing
Fasted; saturation near 100 mcg
Route
Subcutaneous

Storage Instructions

Lyophilized
−20 °C long term (18–24 months); stable at room temperature for short transit.
Reconstituted
2–8 °C refrigerated; use within 4 weeks.
Light
Protect from direct light; keep in the original carton.
Freeze/Thaw
Avoid repeat freeze–thaw cycles after reconstitution.

Important Notes

  • Expect significant hunger — this can be the goal or a drawback depending on the protocol.
  • Keep doses near saturation (~100 mcg).

How This Works

GHRP-6 activates the GHS-R1a ghrelin receptor, releasing GH and robustly stimulating appetite (its most distinctive feature). Like other GHRPs it suppresses somatostatin and synergises with GHRH analogs, but it is the least selective of the family, with the strongest orexigenic signal and some cortisol/prolactin activity at higher doses.

Potential Benefits & Side Effects

Reported in research
  • Strong GH pulse
  • Marked appetite stimulation
  • Possible cytoprotective/gut-motility effects studied
  • Synergy with GHRH analogs
Possible considerations
  • Very pronounced appetite increase
  • Water retention
  • Cortisol/prolactin elevation at higher doses
  • Head-rush and flushing
  • Tingling

Lifestyle Factors

  • Adequate hydration and 7–9 h of sleep are standard controls in most research protocols.
  • Consistent dose timing improves the reliability of any self-tracked endpoints.
  • Maintain a clean, sterile workflow for every draw to avoid contamination.

Injection Technique

  1. 1Wash hands, then prep the vial top and the target site with separate alcohol swabs.
  2. 2Pinch a subcutaneous skin fold (abdomen, ~2 inches from the navel) and insert at 45–90°.
  3. 3Depress the plunger slowly over 3–5 seconds, hold 5 seconds, then withdraw.
  4. 4Rotate sites each administration and dispose of the syringe in a sharps container.

Frequently Asked Questions

Third-party HPLC testing

CG Labz Verified Batches

No published batches yet.

Research Disclaimer

All compounds are supplied strictly for laboratory research. Dosing figures below summarize ranges reported in published preclinical and clinical literature for reference purposes only. CG Labz does not provide medical advice or individualized dosing recommendations.

Peer-reviewed literature

References

  1. [1] Endocrine Reviews
    Bowers C.Y. et al. GH-releasing peptide (GHRP) family.
    View Source